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Save the Date – 2024 CTO Conference
November 6-8, 2024
Clinical Trials Ontario will be hosting its annual conference in-person in Toronto, ON. We look forward to connecting with our community to collaborate and exchange knowledge.
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Creating Account
Login
Application Process
Manuals & Guides
Video Tutorials
Training Webinars
REB Qualification
Templates & Forms
SOPs
Policies & Legal
Video Tutorials
Applicants
16 Videos
Getting Started with CTO Stream
1:49
Introduction to the Work Area
6:38
Creating a New Project
5:01
Creating a Centre Initial Application (CIA)
5:41
Creating the Centre-specific ICF
5:35
Requesting Signatures
3:18
Responding to Signature Request
3:25
Sending a Correspondence Message to the REB of Record
2:49
Removing a User's Role for an Application or Entire Study
2:48
Identifying the REB of Record for the Study
2:24
The Project Tree Page
5:13
Navigating the Application Form
5:27
Responding to a Request for Modifications
3:39
Transferring Project Ownership
3:03
Post-Approval Applications
7:45
Applicant Side Track Changes
3:39
Topics Covered
Topics Covered
How to register for a CTO Stream applicant account
How to active the your account
Applicant login portal
Topics Covered
Topics Covered
CTO Stream login page
The Navigation Bar
General Tiles
Projects List/Folders
Actions Menu
Topics Covered
Topics Covered
Creating a New Project
Sharing access to the new Project
Provincial-level roles
Topics Covered
Topics Covered
Creating a Centre Initial Application (CIA)
Sharing access to the new Project
Centre-level roles
Topics Covered
Topics Covered
Locating and downloading the Provincially approved ICF template
Downloading DIER and SRERS Administration forms
Creating a site-specific ICF
Uploading your centre-specific ICF into the CIA
Topics Covered
Topics Covered
Requesting a signature for an application
Cancel all signatures and signature requests
How to cancel a single signature request
Topics Covered
Topics Covered
How to find the signature request
How to sign the application
How to sign-off as a delegate
Topics Covered
Topics Covered
What is ‘Correspondence’?
How to send a new Correspondence message
Who is notified when the REB replies
How to view the REB response
Topics Covered
Topics Covered
Explanation of ‘Roles’ in CTO Stream
Identifying which form a user was given their role on
Removing a user’s role from the application or entire study
Verifying role was removed successfully
Topics Covered
Topics Covered
REB of Record selection
When can you view the assigned REB
Why is this important?
How to view the REB of Record for your project
Topics Covered
Topics Covered
Viewing application forms in the Project Tree
The Actions Menu on the Project Tree page
Form status bar
Application form tabs
Topics Covered
Topics Covered
Application form features
Types of questions in the application form
How to make panel comments of form questions
Actions Menu inside the application form
Topics Covered
Topics Covered
Status of the application once sent back for changes
Locating the REB letter which lists required changes
Notifications when application is sent back for changes
Steps to complete when re-submitting an application
Topics Covered
Topics Covered
How to identify the project owner for a study
How to initiate a project transfer request
How to accept a project transfer request
Topics Covered
Topics Covered
Creating Provincial post-approval forms
Creating Centre post-approval forms
Tips for working with amendments
Continuing review reminders
How to unlock and re-submit an approved/acknowledged reportable event
Topics Covered
Topics Covered
Demonstrates how CTO Stream applicants can enable track-changes mode on the form they are working on to view any changes made compared to the previous submission of the form.
Research Ethics Boards (REBs)
11 Videos
Reviewer Comments
4:14
Changing Expiry Date Status and Re-issuing the Approval Letter
4:25
Editing Document Name, Version Date and Version Number of a Submission Document
2:13
Reviewing a CTO Stream Submission
6:01
REB Meetings
9:28
Drafting and Sending the REB Letter
8:32
Correspondence Messages
5:53
Letter Review Pathway
6:26
CTO Stream for REB Members
10:18
REB Staff Tutorial — Part 1
11:50
REB Staff Tutorial — Part 2
11:10
Topics Covered
Topics Covered
Panel Comments vs. Form Comments
Viewing Panel Comments and Form Comments
How to create a Form Comment
How to create Panel Comment
Topics Covered
Topics Covered
Why would we ever need to do this?
Viewing study Status and Expiry Date from the Centres tab
Changing study Status and Expiry Date
Re-issuing the Approval letter
Topics Covered
Topics Covered
How is the REB notified of an error with a Document Name, Version Date or Number?
Where to find the documents attached to the submission (Form Documents)
How to edit Form Documents of a Submission
Topics Covered
Topics Covered
Overview of the Work Area
Open a submission to the Submission Timeline Page
Accessing the submission documents
Table of contents for the form (the Navigation Page)
Printing the form
Inside the application form
Topics Covered
Topics Covered
Viewing upcoming and past meetings for your REB
Explore the Meetings Overview Page
Creating or deleting a meeting
How to assign a submission to a meeting
Assign a submission to a past meeting
Topics Covered
Topics Covered
How to create a draft of the letter & tips for working with letter templates
How to save a copy of the letter draft
How to load the saved letter draft
How to collate reviewer comments into the letter
Sending the letter to the study team
Topics Covered
Topics Covered
What is correspondence?
The Correspondence Tab on the Submission Timeline
How to view and reply to messages sent by the study team
Viewing correspondence messages from archived previous submissions of the form
How to initiate a new correspondence message to the study team
Topics Covered
Topics Covered
An overview of the letter review process
How to assign a letter reviewer
Reviewing a drafted letter as an assigned letter reviewer
How to request changes, or make changes directly to the REB letter
Topics Covered
Topics Covered
Logging in to the review side of the CTO Stream system
Overview of the Work Area
How to access and navigate the CTO Stream submissions
Viewing and making reviewer comments on submissions
Topics Covered
Topics Covered
Overview of the workflow for REB submissions
The tile system of the Work Area
The submission timeline page
Pre-screen step (administrative review)
Topics Covered
Topics Covered
Full board review and how to assign a submission to a meeting
The delegated review process
Recording the decision for the submission
Categorize documents
Setting the study-wide expiry date
Archive Documents
Drafting and Sending Approval Letter
